Biomarkers for monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma
Funding Cycle:
2022-2023Name:
Florentin SpäthType of Award:
Career Development AwardHome Institution:
Umeå University, SwedenHost Institution:
University of Adelaide, AustraliaDescription
In this collaborative research project, we aim to identify and develop blood biomarkers improving MGUS follow-up. To achieve this, blood-based proteomic analysis using untargeted i3-D/LC mass spectrometry in unique prospective longitudinal blood samples (n=880) collected in participants of the Northern Sweden Health and Disease Study (Umeå University, Sweden) is performed. Routine and novel biomarkers will be included in a novel risk score that could help to improve the stratification of MGUS patients.