Biomarkers for monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma

Basic Information

Funding Cycle : 2022-2023

Name : Florentin Späth

Type of Award : Career Development Award

Home Institution : Umeå University, Sweden

Host Institution : University of Adelaide, Australia

Description

In this collaborative research project, we aim to identify and develop blood biomarkers improving MGUS follow-up. To achieve this, blood-based proteomic analysis using untargeted i3-D/LC mass spectrometry in unique prospective longitudinal blood samples (n=880) collected in participants of the Northern Sweden Health and Disease Study (UmeÃ¥ University, Sweden) is performed. Routine and novel biomarkers will be included in a novel risk score that could help to improve the stratification of MGUS patients.

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