Characterizing the emergence of T cell dysfunction as a cause of therapy failure and disease progression in multiple myeloma

Funding Cycle:

2024-2025

Name:

Ross Firestone

Type of Award:

Career Development Award

Home Institution:

Memorial Sloan Kettering Cancer Center

Host Institution:

University of Miami

Description

Using comprehensive immune profiling techniques, I will investigate the role that immune dysfunction plays throughout the myeloma disease course. This includes immune profiling in patients with newly diagnosed multiple myeloma on immunomodulatory drugs as well as in relapsed or refractory multiple myeloma patients receiving bispecific antibodies. Through this immune profiling we hope to identify immune biomarkers predictive of clinical outcomes and identify novel treatment strategies to optimize patient immune function when receiving immune based therapies.

Why Become a Member

The International Myeloma Society is a professional, scientific, and medical society established to bring together clinical and experimental scientists involved in the study of myeloma. The purpose of this society is to promote research, education, clinical studies (including diagnosis and treatment), workshops, conferences, and symposia on all aspects of multiple myeloma worldwide.

The IMS is a membership organization comprised of basic research scientists, and clinical investigators in the field along with physicians and other healthcare practitioners.

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