Early Detection and Intervention in Smoldering Multiple Myeloma: Population-Based Screening and Treatment (Edit-SMM)

Description

The Edit-SMM project aims to revolutionize the management of smoldering multiple myeloma (SMM). Building on the iStopMM study, it seeks to improve early detection and treatment to potentially prevent the progression to full-blown multiple myeloma (MM), enhancing patient outcomes. The Edit-SMM analyzes epidemiological data, assesses the efficacy and safety of early treatments, and employs novel diagnostic techniques like flow cytometry and mass spectrometry. Additionally, it includes genetic studies to elucidate the transition from MGUS to SMM and MM. The significance of this approach lies in its potential to redefine SMM management, aiming for a considerable impact on life expectancy and quality of life for individuals at risk. Preliminary results from the iStopMM study indicate the feasibility of such an approach. The project’s comprehensive strategy combines clinical assessments, laboratory analyses, and ethical considerations to address crucial questions about SMM management and treatment efficacy. Ultimately, Edit-SMM represents a significant effort to improve understanding and treatment of SMM, aiming to prevent the disease’s progression and improve patient outcomes.