Discovering and targeting unprecedented mitochondrial vulnerabilities against multiple myeloma
This research aims to target mitochondrial vulnerabilities in multiple myeloma (MM) by focusing on ClpP, a mitochondrial protease highly expressed in MM cells. Leveraging ClpP’s importance for MM cell survival, the study seeks to understand its function and identify novel mitochondrial vulnerabilities. Using functional geno-proteomics and genetic screening, the research aims to achieve two main … Continued